Edi Rama was responding to two days of protests in Tirana and other cities.
The Balkan nation recently destroyed its own chemical stockpile, and the US had requested that it host the dismantling of Syria's arsenal.
Under the deal brokered by Russia to remove Syria's chemical weapons, it was agreed that they should be destroyed outside the country if possible.
Mr Rama attacked the Albanian opposition for having criticised the government's willingness to consider the idea.
